Our dental practice is now pleased to accelerate your recovery from numbness after routine dental procedures. OraVerse™ is the first and only product of its kind to rapidly reverse the effects of local anesthetics containing a vasoconstrictor so you can feel, speak, smile, and drink normally in approximately half the time.1 OraVerse is not recommended for use in children less than 6 years of age or weighing less than 15 kg (33 lbs).

For more information on this innovative new product, we invite you to visit www.OraVerse.com.

Important Safety Information:
Tachycardia, bradycardia, and cardiac arrhythmias may occur with the use of phentolamine or other alpha-adrenergic blocking agents. Although such effects are uncommon with OraVerse (phentolamine mesylate), clinicians should be alert to the signs and symptoms of these events, particularly in patients with a history of cardiovascular disease. Following parenteral use of phentolamine at doses between 5 to 15 times higher than the recommended dose of OraVerse, myocardial infarction, and cerebrovascular spasm and occlusion have been reported, usually in association with marked hypotensive episodes producing shock-like states.

1 Median time to recovery of normal sensation was reduced by 85 minutes (55%) in the mandible and by 83 minutes (62%) in the maxilla compared to control. Median time to recovery of normal function was reduced by 60 minutes (50%) in the mandible and by 45 minutes (43%) in the maxilla.